This game works across 3 screens right out of the box. Just select Widescreen format in the video options and you can then choose any surround resolution. The game seems to have a small problem with the crosshair. It disappears when in 3 screen mode. Just go to video options while in the game and change the resolution to single screen and then back. The cross hair then will stay untill you exit the game. Hopefully Gearbox will fix that problem with the next patch.
Some screenshots
Some screenshots
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