AP story....
Herpes drug helps control HIV in women, study finds
Treating genital herpes can also help keep the AIDS virus under control in women with both infections, and might reduce the spread of HIV, too, the first major study to test this strategy suggests.
Many people with HIV are also infected with herpes type 2, and scientists have long known that herpes sores on the genitals can make it easier to become infected with the AIDS virus and could increase the risk of transmitting HIV to others.
In the latest study, conducted in Africa and published in today's New England Journal of Medicine, women who took the herpes drug valacyclovir had less HIV in their blood and in their genital secretions.
The study did not look at whether the drug, sold as Valtrex by GlaxoSmithKline PLC, actually reduces transmission of the AIDS virus. However, scientists generally have found that the more virus someone has, the greater the risk of transmission.
Doctors have been looking for novel ways to treat and prevent HIV infection, particularly in poor countries where few can afford modern AIDS drugs and the stigma keeps many from taking them.
Researchers recently found that circumcision lowers the risk of spreading HIV, and they hope the same will prove true of treating herpes.
``It does open some potential avenues to slowing down the HIV epidemic,'' said Dr. Lawrence Corey, a leading herpes researcher at the University of Washington who had no role in the study but has received research grants from Glaxo.
The study involved researchers from France, England and Burkina Faso and was funded by the French national AIDS research agency, ANRS.
There are 4.3 million new HIV infections worldwide each year. Past studies have shown that herpes infections can triple a person's chance of acquiring HIV and can make HIV-positive individuals more infectious.
Treating genital herpes can also help keep the AIDS virus under control in women with both infections, and might reduce the spread of HIV, too, the first major study to test this strategy suggests.
Many people with HIV are also infected with herpes type 2, and scientists have long known that herpes sores on the genitals can make it easier to become infected with the AIDS virus and could increase the risk of transmitting HIV to others.
In the latest study, conducted in Africa and published in today's New England Journal of Medicine, women who took the herpes drug valacyclovir had less HIV in their blood and in their genital secretions.
The study did not look at whether the drug, sold as Valtrex by GlaxoSmithKline PLC, actually reduces transmission of the AIDS virus. However, scientists generally have found that the more virus someone has, the greater the risk of transmission.
Doctors have been looking for novel ways to treat and prevent HIV infection, particularly in poor countries where few can afford modern AIDS drugs and the stigma keeps many from taking them.
Researchers recently found that circumcision lowers the risk of spreading HIV, and they hope the same will prove true of treating herpes.
``It does open some potential avenues to slowing down the HIV epidemic,'' said Dr. Lawrence Corey, a leading herpes researcher at the University of Washington who had no role in the study but has received research grants from Glaxo.
The study involved researchers from France, England and Burkina Faso and was funded by the French national AIDS research agency, ANRS.
There are 4.3 million new HIV infections worldwide each year. Past studies have shown that herpes infections can triple a person's chance of acquiring HIV and can make HIV-positive individuals more infectious.
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