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  • #1

    Transplant rejection fix?

    This is a WHOA! moment.

    Link....

    LOS ANGELES — In what's being called a major advance in organ transplants, doctors say they have developed a technique that could free many patients from having to take anti-rejection drugs for the rest of their lives.

    The treatment involved weakening the patient's immune system, then giving the recipient bone marrow from the person who donated the organ. In one experiment, four of five kidney recipients were off immune-suppressing medicines up to five years later.

    "There's reason to hope these patients will be off drugs for the rest of their lives," said Dr. David Sachs of Massachusetts General Hospital in Boston, who led the research published in Thursday's New England Journal of Medicine.

    Dr. Mordrid
    ----------------------------
    An elephant is a mouse built to government specifications.

    I carry a gun because I can't throw a rock 1,250 fps
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  • #2
    On a related note, something I heard on the news this morning.

    A doctor in Queensland(Aus) treating a liver tranplant patient has found the patients blood group changed an is now compatable with his new liver

    The doctor has been consulting experts all of the world about it and is to see if it has occurred before but they are pretty much stunned.

    This is quite an early report which I may have got slightly wrong and may be BS , but I did hear it on a usualy very reliable national broacaster...defintely a wtf moment.

    Comment

    • #3
      The details, does seem legitimate

      http://www.news.com.au/story/0,23599,23101546-1702,00.html?from=public_rss



      A YOUNG transplant patient has defied medical science by spontaneously switching blood types and taking on her donor's immune system

      NSW teenager Demi Brennan is believed to be the first person in the world to completely accept a donated organ to the extent where her immune system entirely changed.

      Demi, now 15, suffered liver failure and had a liver transplant at the age of nine in 2001.

      Several months on from the transplant, her doctors at Westmead Children's Hospital say theywere shocked to discover her blood type had changed to match the blood type of her deceased male donor.

      On closer inspection, specialists found that stem cells from the donor liver had penetrated her bone marrow, effectively resulting in a naturally occurring bone marrow transplant.

      Her doctor, Michael Stormon, said she was able to come off the anti-rejection drugs which most transplant patients needed to take for the rest of their lives.

      "We were stunned, absolutely stunned, and also very puzzled," said Dr Stormon, who reported the case in the New England Journal of Medicine.

      "Even going through the literature and seeking advice internationally we weren't able to find any other cases like it."

      Demi's mother, Kerrie Mills, described it as "miraculous", and Dr Stormon agreed it was "still highly difficult to explain at this stage".

      "We're not sure the reasons behind why this has happened but it may be that a complex range of circumstances have aligned to bring it about," he said.

      "Now the task is to find out what those are so we can replicate them and allow other transplant patients to has such a complete acceptance."

      A team of scientists has started research into the case, with hopes their findings will improve treatments and outcomes for other transplant patients.
      looks like we might have a few breakthroughs in the pipeline

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      • #4
        Jezzzz....
        Dr. Mordrid
        ----------------------------
        An elephant is a mouse built to government specifications.

        I carry a gun because I can't throw a rock 1,250 fps

        Comment

        • #5
          This is awesome... but isn't giving bone marrow one of the most painful things you can possibly do? I have NOTHING but respect for someone that goes through with it.. but how universal is something like this likely to be?
          Wikipedia and Google.... the needles to my tangent habit.
          ________________________________________________

          That special feeling we get in the cockles of our hearts, Or maybe below the cockles, Maybe in the sub-cockle area, Maybe in the liver, Maybe in the kidneys, Maybe even in the colon, We don't know.

          Comment

          • #6
            Originally posted by Claymonkey View Post
            This is awesome... but isn't giving bone marrow one of the most painful things you can possibly do? I have NOTHING but respect for someone that goes through with it.. but how universal is something like this likely to be?
            It also means that the transplant must come from a live donor.
            Still, progress is progress, and this will lead to some imaginative solutions.
            Chuck
             秋音的爸爸

            Comment

            • #7
              oh no doubt! I don't mean to make my concerns for the procedure make this any less of an amazing discovery!
              Wikipedia and Google.... the needles to my tangent habit.
              ________________________________________________

              That special feeling we get in the cockles of our hearts, Or maybe below the cockles, Maybe in the sub-cockle area, Maybe in the liver, Maybe in the kidneys, Maybe even in the colon, We don't know.

              Comment

              • #8
                Well that... and bone marrow extraction isn't exactly painful if you're a donor at death....
                Wikipedia and Google.... the needles to my tangent habit.
                ________________________________________________

                That special feeling we get in the cockles of our hearts, Or maybe below the cockles, Maybe in the sub-cockle area, Maybe in the liver, Maybe in the kidneys, Maybe even in the colon, We don't know.

                Comment

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