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Faecal transplants have occasionally been used to treat patients with C. difficile infections as a last resort, with a 75% success rate. Recent research on mice has shown great progress and it is now being used experimentally on humans to treat a range of other diseases where usual treatment has failed, such as clinical aggressiveness, diabetes (II), obesity, Crohn's disease, autism, attention disorders, colonic cancer, IBS etc.
The procedure is that healthy persons whose medical history has shown traits opposed to the disease being targeted donate their stools. These are liquidised with sterile water in a blender and 1-1.5 l are filled into syringes. Meanwhile the patient is prepared by a series of enemas, purgatives etc. so that his alimentary canal is completely emptied and washed clean. A tube is inserted through his nose and ends up in his small intestine. The sh*tty solution is then slowly injected into the tube. The patient then has a meal. The research has shown that the intestinal microbotia are often largely contributory to the disease being treated and, by eliminating them and transplanting a different mix of microbotia, a cure is often possible.
Last night, the Swiss TV ran a programme (in French) on the latest research in faecal transplants at http://www.rts.ch/emissions/36-9/449...ouvernent.html showing some disgusting things including the treatment of patients (WARNING: not for those easily disgusted). One patient mentioned that since receiving the treatment, his stools had a different smell! In most cases, there is no reversion to the old microbiota. Thank goodness we don't have smellovision!
Apparently, our natural microbiota makeup is determined from the mother at birth and varies between babies from vaginal and caesarean birth and stabilises after a few years for life (unless transplanted, of course).
The procedure is that healthy persons whose medical history has shown traits opposed to the disease being targeted donate their stools. These are liquidised with sterile water in a blender and 1-1.5 l are filled into syringes. Meanwhile the patient is prepared by a series of enemas, purgatives etc. so that his alimentary canal is completely emptied and washed clean. A tube is inserted through his nose and ends up in his small intestine. The sh*tty solution is then slowly injected into the tube. The patient then has a meal. The research has shown that the intestinal microbotia are often largely contributory to the disease being treated and, by eliminating them and transplanting a different mix of microbotia, a cure is often possible.
Last night, the Swiss TV ran a programme (in French) on the latest research in faecal transplants at http://www.rts.ch/emissions/36-9/449...ouvernent.html showing some disgusting things including the treatment of patients (WARNING: not for those easily disgusted). One patient mentioned that since receiving the treatment, his stools had a different smell! In most cases, there is no reversion to the old microbiota. Thank goodness we don't have smellovision!
Apparently, our natural microbiota makeup is determined from the mother at birth and varies between babies from vaginal and caesarean birth and stabilises after a few years for life (unless transplanted, of course).
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